literature review CPP/Bioportide technologies have the capcity to reach intracellular sites that may be intractable targets for conventional drugs. Moreover, it is likely that many bioportides achieve a biological influence by a dominant-negative action upon protein-proitein interactions (PPIs). Your next task is to choose a protein or a PPI interface that might be a useful target for therapeutic manipulation. There are of course many possibilities and I am keen for you to choose your own! Now imgaine you are tasked by a pharmaceutical company to develop a strategy, employing CPPs/Bioportides, to manipulate that intracellular target. You will need to produde a report to pass on to the peptide synthesis team highlighting sequences of peptides that can be screened as potential therapeutics. These might be inert CPPs attached to a bioactive peptide seuquence or a bioportide that is predicted to be both cell penetrant and bioactive. Your project write-up is essentially that report. The res

literature review CPP/Bioportide technologies have the capcity to reach intracellular sites that may be intractable targets for conventional drugs. Moreover, it is likely that many bioportides achieve a biological influence by a dominant-negative action upon protein-proitein interactions (PPIs). Your next task is to choose a protein or a PPI interface that might be a useful target for therapeutic manipulation. There are of course many possibilities and I am keen for you to choose your own! Now imgaine you are tasked by a pharmaceutical company to develop a strategy, employing CPPs/Bioportides, to manipulate that intracellular target. You will need to produde a report to pass on to the peptide synthesis team highlighting sequences of peptides that can be screened as potential therapeutics. These might be inert CPPs attached to a bioactive peptide seuquence or a bioportide that is predicted to be both cell penetrant and bioactive. Your project write-up is essentially that report. The res

This project will investigatw changes in epigenetics signatures associated with depression and associated changes in gene and protein expression . the student will learn arange of experimental techniques including neural stem cell culture and chromatin immunoprecipitation and arange of bioinformatics skills including analysis of genome-wide sequencing data.

present the results of your analysis of the experimental samples in a separate graph. You should describe your results (500 words maximum). You should then give a brief discussion and conclusion for your findings (500 words maximum). for this particular coursework I need 2 graphs plotted with Sigmaplot.

present the results of your analysis of the experimental samples in a separate graph. You should describe your results (500 words maximum). You should then give a brief discussion and conclusion for your findings (500 words maximum). for this particular coursework I need 2 graphs plotted with Sigmaplot.